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Turning cancer's metabolic plasticity into fragility- an evolving paradigm

In an elegant report, Corbet et al(1) recently demonstrated the much needed insight to exploit cancer's metabolic reprogramming for potential therapeutic intervention. In brief, the findings underscore the principle that abrogation of mitochondrial pyruvate metabolism upregulates glycolysis, an...

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Pubblicato in:Cancer Biol Ther
Autore principale: Ganapathy-Kanniappan, Shanmugasundaram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154855/
https://ncbi.nlm.nih.gov/pubmed/29723104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1471441
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