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Rac1 repression reverses chemoresistance by targeting tumor metabolism
Tumor metabolism is exemplified by the increased rate of glucose utilization, a biochemical signature of cancer cells. The enhanced glucose hydrolysis enabled by the augmentation of glycolytic flux and the pentose phosphate pathway (PPP) plays a pivotal role in the growth and survival of neoplastic...
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| Udgivet i: | Cancer Biol Ther |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7583477/ https://ncbi.nlm.nih.gov/pubmed/32866423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2020.1809923 |
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