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Protein kinase Cι: A versatile oncogene in the lung
We have recently demonstrated that protein kinase Cι (PKCι) promotes a stem-like, tumor-initiating cell phenotype in KRAS-driven lung adenocarcinoma by activating a novel ELF3-NOTCH3 signaling axis.(1) Combined PKCι and NOTCH inhibition was identified as a novel strategy for the treatment of KRAS-dr...
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| Udgivet i: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154840/ https://ncbi.nlm.nih.gov/pubmed/30263934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1190886 |
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