Interleukin-12p35 Knock Out Aggravates Doxorubicin-Induced Cardiac Injury and Dysfunction by Aggravating the Inflammatory Response, Oxidative Stress, Apoptosis and Autophagy in Mice

BACKGROUND: Recent evidence has demonstrated that interleukin 12p35 knockout (IL-12p35 KO) is involved in cardiac diseases by regulating the inflammatory response. The involvement of inflammatory cells has also been observed in doxorubicin (DOX)-induced cardiac injury. This study aimed to investigat...

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Publicat a:EBioMedicine
Autors principals: Ye, Jing, Huang, Ying, Que, Bin, Chang, Chao, Liu, Wenjing, Hu, Haiying, Liu, Ling, Shi, Ying, Wang, Yuan, Wang, Menglong, Zeng, Tao, Zhen, Wang, Xu, Yao, Shi, Lei, Liu, Jianfang, Jiang, Huimin, Ye, Di, Lin, Yingzhong, Wan, Jun, Ji, Qingwei
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154773/
https://ncbi.nlm.nih.gov/pubmed/30228093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.06.009
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