Modulation of genomic and epigenetic end-points by celecoxib

Celecoxib, a nonsteroidal anti-inflammatory drug that selectively targets cyclooxygenase-2, is a promising cancer chemopreventive agent. However, safety concerns have been raised in clinical trials evaluating its ability to prevent colorectal adenomas. The rationale for the herein reported studies w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Izzotti, Alberto, La Maestra, Sebastiano, Micale, Rosanna T., Pulliero, Alessandra, Geretto, Marta, Balansky, Roumen, De Flora, Silvio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154745/
https://ncbi.nlm.nih.gov/pubmed/30263093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26062
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