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Pharmacological Modulation of Lung Carcinogenesis in Smokers: Preclinical and Clinical Evidence

Many drugs in common use possess pleiotropic properties that make them capable of interfering with carcinogenesis mechanisms. We discuss here the ability of pharmacological agents to mitigate the pulmonary carcinogenicity of mainstream cigarette smoke. The evaluated agents included antiinflammatory...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: De Flora, Silvio, Ganchev, Gancho, Iltcheva, Marietta, La Maestra, Sebastiano, Micale, Rosanna T., Steele, Vernon E., Balansky, Roumen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728041/
https://ncbi.nlm.nih.gov/pubmed/26726119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.11.003
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