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Synthesis of Pyrrolo[1,2-a]pyrimidine Enantiomers via Domino Ring-Closure followed by Retro Diels-Alder Protocol

From 2-aminonorbornene hydroxamic acids, a simple and efficient method for the preparation of pyrrolo[1,2-a]pyrimidine enantiomers is reported. The synthesis is based on domino ring-closure followed by microwave-induced retro Diels-Alder (RDA) protocols, where the chirality of the desired products i...

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Publicado en:Molecules
Main Authors: Fekete, Beáta, Palkó, Márta, Haukka, Matti, Fülöp, Ferenc
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154686/
https://ncbi.nlm.nih.gov/pubmed/28406463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040613
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