Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is...

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Publicat a:Molecules
Autors principals: Felippe Gonçalves-de-Albuquerque, Cassiano, Ribeiro Silva, Adriana, Ignácio da Silva, Camila, Caire Castro-Faria-Neto, Hugo, Burth, Patrícia
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154632/
https://ncbi.nlm.nih.gov/pubmed/28430151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040578
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