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Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol
BACKGROUND: Na/K-ATPase (NKA) is inhibited by perillyl alcohol (POH), a monoterpene used in the treatment of tumors, including brain tumors. The NKA α(1) subunit is known to be superexpressed in glioblastoma cells (GBM). This isoform is embedded in caveolar structures and is probably responsible for...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432499/ https://ncbi.nlm.nih.gov/pubmed/25976744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0374-5 |
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