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Synthesis and Antiproliferative Activity of Novel All-Trans-Retinoic Acid-Podophyllotoxin Conjugate towards Human Gastric Cancer Cells

With the purpose of creating a multifunctional drug for gastric cancer treatment, a novel all-trans-retinoic acid (ATRA) conjugate with podophyllotoxin (PPT) was designed and synthesized, and its in vitro antiproliferative activity was evaluated against human gastric cancer cell lines using CCK-8 as...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Lei, Wang, Jing, Liu, Lai, Zheng, Chengyue, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154554/
https://ncbi.nlm.nih.gov/pubmed/28420180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040628
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