Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development

Since its original isolation in 2009, Candida auris has spread across the globe as a causative agent of invasive candidiasis. C. auris is typically intrinsically resistant to fluconazole and can also be resistant to echinocandins and even amphotericin B. Thus, there is an urgent need to find new tre...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Wall, Gina, Chaturvedi, Ashok K., Wormley, Floyd L., Wiederhold, Nathan P., Patterson, Hoja P., Patterson, Thomas F., Lopez-Ribot, José L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Susceptibility
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153848/
https://ncbi.nlm.nih.gov/pubmed/30104269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01084-18
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