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Screening a Repurposing Library for Inhibitors of Multidrug-Resistant Candida auris Identifies Ebselen as a Repositionable Candidate for Antifungal Drug Development

Since its original isolation in 2009, Candida auris has spread across the globe as a causative agent of invasive candidiasis. C. auris is typically intrinsically resistant to fluconazole and can also be resistant to echinocandins and even amphotericin B. Thus, there is an urgent need to find new tre...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wall, Gina, Chaturvedi, Ashok K., Wormley, Floyd L., Wiederhold, Nathan P., Patterson, Hoja P., Patterson, Thomas F., Lopez-Ribot, José L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153848/
https://ncbi.nlm.nih.gov/pubmed/30104269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01084-18
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