Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus

Zika virus (ZIKV) has been linked to the development of microcephaly in newborns, as well as Guillain-Barré syndrome. There are currently no drugs available to treat ZIKV infection, and accordingly, there is an unmet medical need for the discovery of new therapies. High-throughput drug screening eff...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bernatchez, Jean A., Yang, Zunhua, Coste, Michael, Li, Jerry, Beck, Sungjun, Liu, Yan, Clark, Alex E., Zhu, Zhe, Luna, Lucas A., Sohl, Christal D., Purse, Byron W., Li, Rongshi, Siqueira-Neto, Jair L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153842/
https://ncbi.nlm.nih.gov/pubmed/30061280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00725-18
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