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Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase

Carbohydrate hydrolyzing α‐glucosidases are commonly found in microorganisms present in the human intestine microbiome. We have previously reported crystal structures of an α‐glucosidase from the human gut bacterium Blaubia (Ruminococcus) obeum (Ro‐αG1) and its substrate preference/specificity switc...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Tan, Kemin, Tesar, Christine, Wilton, Rosemarie, Jedrzejczak, Robert P., Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153411/
https://ncbi.nlm.nih.gov/pubmed/29761590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3444
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