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Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase

Carbohydrate hydrolyzing α‐glucosidases are commonly found in microorganisms present in the human intestine microbiome. We have previously reported crystal structures of an α‐glucosidase from the human gut bacterium Blaubia (Ruminococcus) obeum (Ro‐αG1) and its substrate preference/specificity switc...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Tan, Kemin, Tesar, Christine, Wilton, Rosemarie, Jedrzejczak, Robert P., Joachimiak, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153411/
https://ncbi.nlm.nih.gov/pubmed/29761590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3444
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