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Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase

Carbohydrate hydrolyzing α‐glucosidases are commonly found in microorganisms present in the human intestine microbiome. We have previously reported crystal structures of an α‐glucosidase from the human gut bacterium Blaubia (Ruminococcus) obeum (Ro‐αG1) and its substrate preference/specificity switc...

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Bibliografski detalji
Izdano u:Protein Sci
Glavni autori: Tan, Kemin, Tesar, Christine, Wilton, Rosemarie, Jedrzejczak, Robert P., Joachimiak, Andrzej
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153411/
https://ncbi.nlm.nih.gov/pubmed/29761590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3444
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