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A paternal methyl donor depleted diet leads to increased anxiety- and depression-like behavior in adult rat offspring

Epigenetic mechanisms such as DNA methylation elicit lasting changes in gene expression and likely mediate gene–environment interactions that shape brain development, behavior, and emotional health. Myriad environmental factors influence DNA methylation, including methyl donor content in the paterna...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: McCoy, Chelsea R., Jackson, Nateka L., Brewer, Rachel L., Moughnyeh, Mohamad M., Smith, Daniel L., Clinton, Sarah M.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153370/
https://ncbi.nlm.nih.gov/pubmed/29945927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180730
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