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A paternal methyl donor depleted diet leads to increased anxiety- and depression-like behavior in adult rat offspring

Epigenetic mechanisms such as DNA methylation elicit lasting changes in gene expression and likely mediate gene–environment interactions that shape brain development, behavior, and emotional health. Myriad environmental factors influence DNA methylation, including methyl donor content in the paterna...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: McCoy, Chelsea R., Jackson, Nateka L., Brewer, Rachel L., Moughnyeh, Mohamad M., Smith, Daniel L., Clinton, Sarah M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153370/
https://ncbi.nlm.nih.gov/pubmed/29945927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180730
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