GPS2 Deficiency Triggers Maladaptive White Adipose Tissue Expansion in Obesity via HIF1A Activation

Hypertrophic white adipose tissue (WAT) represents a maladaptive mechanism linked to the risk for developing type 2 diabetes in humans. However, the molecular events that predispose WAT to hypertrophy are poorly defined. Here, we demonstrate that adipocyte hypertrophy is triggered by loss of the cor...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Drareni, Karima, Ballaire, Raphaëlle, Barilla, Serena, Mathew, Mano J., Toubal, Amine, Fan, Rongrong, Liang, Ning, Chollet, Catherine, Huang, Zhiqiang, Kondili, Maria, Foufelle, Fabienne, Soprani, Antoine, Roussel, Ronan, Gautier, Jean-François, Alzaid, Fawaz, Treuter, Eckardt, Venteclef, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153369/
https://ncbi.nlm.nih.gov/pubmed/30208320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.032
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker