Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

Atherosclerosis is a complex disease that involves alterations in lipoprotein metabolism and inflammation. Protein and lipid glycosylation events, such as sialylation, contribute to the development of atherosclerosis and are regulated by specific glycosidases, including sialidases. To evaluate the e...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: White, Elizabeth J., Gyulay, Gabriel, Lhoták, Šárka, Szewczyk, Magdalena M., Chong, Taryne, Fuller, Mark T., Dadoo, Omid, Fox-Robichaud, Alison E., Austin, Richard C., Trigatti, Bernardo L., Igdoura, Suleiman A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153285/
https://ncbi.nlm.nih.gov/pubmed/30097518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004589
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