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Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice

Lipoprotein metabolism is an important contributing factor in the development and progression of atherosclerosis. Plasma lipoproteins and their receptors are heavily glycosylated and sialylated, and levels of sialic acids modulate their biological functions. Sialylation is controlled by the activiti...

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Библиографические подробности
Главные авторы: Yang, Abraham, Gyulay, Gabriel, Mitchell, Mark, White, Elizabeth, Trigatti, Bernardo L., Igdoura, Suleiman A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Biochemistry and Molecular Biology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494259/
https://ncbi.nlm.nih.gov/pubmed/22984145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M027300
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