Evaluating the broad-spectrum efficacy of the acetylcholinesterase oximes reactivators MMB4 DMS, HLö-7 DMS, and 2-PAM Cl against phorate oxon, sarin, and VX in the Hartley guinea pig

Organophosphorus (OP) compounds, including pesticides and chemical warfare nerve agents (CWNA), are threats to the general population as possible weapons of terrorism or by accidental exposure whether through inadvertent release from manufacturing facilities or during transport. To mitigate the toxi...

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Veröffentlicht in:Neurotoxicology
Hauptverfasser: Wilhelm, Christina M., Snider, Thomas H., Babin, Michael C., Platoff, Gennady E., Jett, David A., Yeung, David T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153028/
https://ncbi.nlm.nih.gov/pubmed/30056178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2018.07.014
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