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Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients

AIMS: IgA nephropathy, the most common primary glomerulonephritis worldwide, is characterized by glomerular deposition of galactose-deficient IgA1 and elevated serum levels of this IgA1 glycoform. Current ELISA methods lack sensitivity to assess galactose deficiency using small amounts of IgA1, whic...

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Detalhes bibliográficos
Publicado no:Biotechniques
Main Authors: Reily, Colin, Rizk, Dana V, Julian, Bruce A, Novak, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152805/
https://ncbi.nlm.nih.gov/pubmed/30091383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/btn-2018-0042
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