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3D Pharmacophore-Based Virtual Screening and Docking Approaches toward the Discovery of Novel HPPD Inhibitors

p-Hydroxyphenylpyruvate dioxygenase (HPPD) is not only the useful molecular target in treating life-threatening tyrosinemia type I, but also an important target for chemical herbicides. A combined in silico structure-based pharmacophore and molecular docking-based virtual screening were performed to...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Fu, Ying, Sun, Yi-Na, Yi, Ke-Han, Li, Ming-Qiang, Cao, Hai-Feng, Li, Jia-Zhong, Ye, Fei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152767/
https://ncbi.nlm.nih.gov/pubmed/28598377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060959
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