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Bioactive Natural Product and Superacid Chemistry for Lead Compound Identification: A Case Study of Selective hCA III and L-Type Ca(2+) Current Inhibitors for Hypotensive Agent Discovery

Dodoneine (Ddn) is one of the active compounds identified from Agelanthus dodoneifolius, which is a medicinal plant used in African pharmacopeia and traditional medicine for the treatment of hypertension. In the context of a scientific program aiming at discovering new hypotensive agents through the...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Carreyre, Hélène, Carré, Grégoire, Ouedraogo, Maurice, Vandebrouck, Clarisse, Bescond, Jocelyn, Supuran, Claudiu T., Thibaudeau, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152723/
https://ncbi.nlm.nih.gov/pubmed/28561785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22060915
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