CASP4/caspase-11 promotes autophagosome formation in response to bacterial infection

CASP4/caspase-11-dependent inflammasome activation is important for the clearance of various Gram-negative bacteria entering the host cytosol. Additionally, CASP4 modulates the actin cytoskeleton to promote the maturation of phagosomes harboring intracellular pathogens such as Legionella pneumophila...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Krause, Kathrin, Caution, Kyle, Badr, Asmaa, Hamilton, Kaitlin, Saleh, Abdulmuti, Patel, Khushbu, Seveau, Stephanie, Hall-Stoodley, Luanne, Hegazi, Rana, Zhang, Xiaoli, Gavrilin, Mikhail A., Amer, Amal O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152495/
https://ncbi.nlm.nih.gov/pubmed/30165781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1491494
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