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Role of STAT3 in skin fibrosis and transforming growth factor beta signalling

OBJECTIVE: SSc is an autoimmune disease characterized by progressive fibrosis of the skin and internal organs. IL-6 and related cytokines that signal through STAT3 have been implicated in the pathogenesis of SSc and mouse models of fibrosis. The aim of this study was to investigate the efficacy of i...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Pedroza, Mesias, To, Sarah, Assassi, Shervin, Wu, Minghua, Tweardy, David, Agarwal, Sandeep K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152423/
https://ncbi.nlm.nih.gov/pubmed/29029263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kex347
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