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Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model

OBJECTIVE: Systemic sclerosis (SSc) is an autoimmune disease clinically manifesting as progressive fibrosis of the skin and internal organs. Cadherin-11 (CDH11) expression is increased in fibrotic skin and lung tissue. Targeting CDH11 may be an effective approach to treating fibrosis. We hypothesize...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pedroza, Mesias, Welschhans, Robert L., Agarwal, Sandeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675431/
https://ncbi.nlm.nih.gov/pubmed/29112946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187109
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