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Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway

The artemisinin compounds, which are well-known for their potent therapeutic antimalarial activity, possess in vivo and in vitro antitumor effects. Although the anticancer effect of artemisinin compounds has been extensively reported, the precise mechanisms underlying its cytotoxicity remain under i...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Chen, Xiao, Wong, Yin Kwan, Lim, Teck Kwang, Lim, Wei Hou, Lin, Qingsong, Wang, Jigang, Hua, Zichun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152404/
https://ncbi.nlm.nih.gov/pubmed/28786914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081272
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