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ASC acts in a caspase-1-independent manner to worsen acute pneumonia caused by Pseudomonas aeruginosa
Purpose. Pseudomonas aeruginosa expresses a type III secretion system (T3SS) that activates the host inflammasome-mediated immune response. We examined the role of inflammasome activation in severe infection outcomes. Methods. We infected C57BL/6 (B6) mice lacking inflammasome components ASC or casp...
Shranjeno v:
| izdano v: | J Med Microbiol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Microbiology Society
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152396/ https://ncbi.nlm.nih.gov/pubmed/29957172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.000782 |
| Oznake: |
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