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Synthesis and Evaluation of Novel Benzofuran Derivatives as Selective SIRT2 Inhibitors
A series of benzofuran derivatives were designed and synthesized, and their inhibitory activites were measured against the SIRT1–3. The enzymatic assay showed that all the compounds showed certain anti-SIRT2 activity and selective over SIRT1 and SIRT3 with IC(50) (half maximal inhibitory concentrati...
Tallennettuna:
| Julkaisussa: | Molecules |
|---|---|
| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152376/ https://ncbi.nlm.nih.gov/pubmed/28805748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081348 |
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