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Synthesis and radioprotective effects of novel benzyl naphthyl sulfoxide (sulfone) derivatives transformed from Ex-RAD

In this work, a series of novel benzyl naphthyl sulfoxides (sulfones) derived from Ex-RAD were designed and synthesized as potential radioprotective agents. Some of the compounds considerably protected HUVECs against (60)Co γ-irradiation, accompanied by the absence of cytotoxicity. Compared to Ex-RA...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Tang, Lin, Peng, Tao, Wang, Gang, Wen, Xiaoxue, Sun, Yunbo, Zhang, Shouguo, Liu, Shuchen, Wang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072350/
https://ncbi.nlm.nih.gov/pubmed/30108953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00573c
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