Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist

β3-adrenergic receptor (AR) agonists are approved to treat only overactive bladder. However, rodent studies suggest that these drugs could have other beneficial effects on human metabolism. We performed tissue receptor profiling and showed that the human β3-AR mRNA is also highly expressed in gallbl...

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Vydáno v:Diabetes
Hlavní autoři: Baskin, Alison S., Linderman, Joyce D., Brychta, Robert J., McGehee, Suzanne, Anflick-Chames, Esti, Cero, Cheryl, Johnson, James W., O’Mara, Alana E., Fletcher, Laura A., Leitner, Brooks P., Duckworth, Courtney J., Huang, Shan, Cai, Hongyi, Garraffo, H. Martin, Millo, Corina M., Dieckmann, William, Tolstikov, Vladimir, Chen, Emily Y., Gao, Fei, Narain, Niven R., Kiebish, Michael A., Walter, Peter J., Herscovitch, Peter, Chen, Kong Y., Cypess, Aaron M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2018
Témata:
Pharmacology and Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152342/
https://ncbi.nlm.nih.gov/pubmed/29980535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0462
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