Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist

β3-adrenergic receptor (AR) agonists are approved to treat only overactive bladder. However, rodent studies suggest that these drugs could have other beneficial effects on human metabolism. We performed tissue receptor profiling and showed that the human β3-AR mRNA is also highly expressed in gallbl...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Baskin, Alison S., Linderman, Joyce D., Brychta, Robert J., McGehee, Suzanne, Anflick-Chames, Esti, Cero, Cheryl, Johnson, James W., O’Mara, Alana E., Fletcher, Laura A., Leitner, Brooks P., Duckworth, Courtney J., Huang, Shan, Cai, Hongyi, Garraffo, H. Martin, Millo, Corina M., Dieckmann, William, Tolstikov, Vladimir, Chen, Emily Y., Gao, Fei, Narain, Niven R., Kiebish, Michael A., Walter, Peter J., Herscovitch, Peter, Chen, Kong Y., Cypess, Aaron M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2018
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152342/
https://ncbi.nlm.nih.gov/pubmed/29980535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0462
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