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Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase
Lactoferrin (LF) is a well-known multifunctional protein. In this study, we report the inhibitory potency of bovine LF (bLF) on catechol-O-methyltransferase (COMT), which catalyzes methylation of catechol substrates. We found that bLF binds to and inhibits COMT using its N-terminal region. An N-term...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152271/ https://ncbi.nlm.nih.gov/pubmed/28825621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081373 |
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