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Inhibitors of the Detoxifying Enzyme of the Phytoalexin Brassinin Based on Quinoline and Isoquinoline Scaffolds

The detoxification of the phytoalexin brassinin to indole-3-carboxaldehyde and S-methyl dithiocarbamate is catalyzed by brassinin oxidase (BOLm), an inducible fungal enzyme produced by the plant pathogen Leptosphaeria maculans. Twenty-six substituted quinolines and isoquinolines are synthesized and...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Pedras, M. Soledade C., Abdoli, Abbas, Sarma-Mamillapalle, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152025/
https://ncbi.nlm.nih.gov/pubmed/28805743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081345
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