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Applications of PNA-Based Artificial Restriction DNA Cutters

More than ten years ago, artificial restriction DNA cutters were developed by combining two pseudo-complementary peptide nucleic acid (pcPNA) strands with either Ce(IV)/EDTA or S1 nuclease. They have remarkably high site-specificity and can cut only one predetermined site in the human genome. In thi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Shigi, Narumi, Sumaoka, Jun, Komiyama, Makoto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151779/
https://ncbi.nlm.nih.gov/pubmed/28934140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101586
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