Synthesis of Chiral TFA-Protected α-Amino Aryl-Ketone Derivatives with Friedel–Crafts Acylation of α-Amino Acid N-Hydroxysuccinimide Ester

Chiral N-protected α-amino aryl-ketones are one of the useful precursors used in the synthesis of various biologically active compounds and can be constructed via Friedel–Crafts acylation of N-protected α-amino acids. One of the drawbacks of this reaction is the utilization of toxic, corrosive and m...

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Publicado en:Molecules
Autores principales: Tachrim, Zetryana Puteri, Oida, Kazuhiro, Ikemoto, Haruka, Ohashi, Fumina, Kurokawa, Natsumi, Hayashi, Kento, Shikanai, Mami, Sakihama, Yasuko, Hashidoko, Yasuyuki, Hashimoto, Makoto
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151496/
https://ncbi.nlm.nih.gov/pubmed/29039791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101748
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