Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway

Treatment of septic acute kidney injury (AKI) has still been beyond satisfaction, although anti-inflammatory therapy is beneficial for sepsis-induced AKI. Compound 5b was derived from natural pyranochalcones and exhibited potent anti-inflammatory activity in adjuvant-induced arthritis. In this study...

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Vydáno v:Molecules
Hlavní autoři: Shi, Min, Zeng, Xiaoxi, Guo, Fan, Huang, Rongshuang, Feng, Yanhuan, Ma, Liang, Zhou, Li, Fu, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151422/
https://ncbi.nlm.nih.gov/pubmed/28994737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101683
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