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Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

Toll-like receptor 4 (TLR4) signaling in the brain mediates autoimmune responses and induces neuroinflammation that results in neurodegenerative diseases, such as Alzheimer’s disease (AD). The plant hormone osmotin inhibited lipopolysaccharide (LPS)-induced TLR4 downstream signaling, including activ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Badshah, Haroon, Ali, Tahir, Kim, Myeong Ok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837357/
https://ncbi.nlm.nih.gov/pubmed/27093924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24493
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