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Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

The pathological hallmarks of Alzheimer’s disease (AD) include amyloid beta (Aβ) accumulation, neurofibrillary tangle formation, synaptic dysfunction and neuronal loss. In this study, we investigated the neuroprotection of novel osmotin, a plant protein extracted from Nicotiana tabacum that has been...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ali, Tahir, Yoon, Gwang Ho, Shah, Shahid Ali, Lee, Hae Young, Kim, Myeong Ok
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484370/
https://ncbi.nlm.nih.gov/pubmed/26118757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11708
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