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COX Inhibition Profile and Molecular Docking Studies of Some 2-(Trimethoxyphenyl)-Thiazoles

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used therapeutic agents that exhibit frequent and sometimes severe adverse effects, including gastrointestinal ulcerations and cardiovascular disorders. In an effort to obtain safer NSAIDs, we assessed the direct cyclooxygenase (COX) inhibi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Oniga, Smaranda Dafina, Pacureanu, Liliana, Stoica, Cristina Ioana, Palage, Mariana Doina, Crăciun, Alexandra, Rusu, Laurentiu Răzvan, Crisan, Elena-Luminita, Araniciu, Cătălin
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151395/
https://ncbi.nlm.nih.gov/pubmed/28891941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091507
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