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Design, Synthesis and Biological Evaluation of New Piperazin-4-yl-(acetyl-thiazolidine-2,4-dione) Norfloxacin Analogues as Antimicrobial Agents

In an effort to improve the antimicrobial activity of norfloxacin, a series of hybrid norfloxacin–thiazolidinedione molecules were synthesized and screened for their direct antimicrobial activity and their anti-biofilm properties. The new hybrids were intended to have a new binding mode to DNA gyras...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Molecules
Κύριοι συγγραφείς: Marc, Gabriel, Araniciu, Cătălin, Oniga, Smaranda Dafina, Vlase, Laurian, Pîrnău, Adrian, Nadăș, George Cosmin, Novac, Cristiana Ștefania, Matei, Ioana Adriana, Chifiriuc, Mariana Carmen, Măruțescu, Luminița, Oniga, Ovidiu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: MDPI 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864599/
https://ncbi.nlm.nih.gov/pubmed/31683749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213959
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