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The use of structural alerts to avoid the toxicity of pharmaceuticals
In order to identify compounds with potential toxicity problems, particular attention is paid to structural alerts, which are high chemical reactivity molecular fragments or fragments that can be transformed via bioactivation by human enzymes into fragments with high chemical reactivity. The concept...
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| Publicado no: | Toxicol Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6151358/ https://ncbi.nlm.nih.gov/pubmed/30258789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2018.08.017 |
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