Fibrolamellar Carcinoma in the Carney Complex: PRKAR1A Loss Instead of the Classic DNAJB1-PRKACA Fusion

Fibrolamellar carcinomas are characterized by activation of protein kinase A, a kinase composed of catalytic and regulatory subunits. PRKACA encodes a catalytic subunit of protein kinase A and almost all fibrolamellar carcinomas have a heterozygous 400kb deletion that leads to the fusion of DNAJB1 a...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Hepatology
Hoofdauteurs: Graham, Rondell P., Lackner, Karoline, Terracciano, Luigi, González-Cantú, Yessica, Maleszewski, Joseph J., Greipp, Patricia T., Simon, Sanford M., Torbenson, Michael S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151295/
https://ncbi.nlm.nih.gov/pubmed/29222914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29719
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items