Fibrolamellar Carcinoma in the Carney Complex: PRKAR1A Loss Instead of the Classic DNAJB1-PRKACA Fusion

Fibrolamellar carcinomas are characterized by activation of protein kinase A, a kinase composed of catalytic and regulatory subunits. PRKACA encodes a catalytic subunit of protein kinase A and almost all fibrolamellar carcinomas have a heterozygous 400kb deletion that leads to the fusion of DNAJB1 a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Hepatology
Autores principales: Graham, Rondell P., Lackner, Karoline, Terracciano, Luigi, González-Cantú, Yessica, Maleszewski, Joseph J., Greipp, Patricia T., Simon, Sanford M., Torbenson, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151295/
https://ncbi.nlm.nih.gov/pubmed/29222914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29719
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares