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Inhibition of Bacterial Gene Transcription with an RpoN-based Stapled Peptide

In response to environmental and other stresses, the σ(54) subunit of bacterial RNA polymerase (RNAP) controls expression of several genes which play a significant role in the virulence of both plant and animal pathogens. Recruitment of σ(54) to RNAP initiates promoter-specific transcription via the...

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發表在:Cell Chem Biol
Main Authors: Payne, Sterling R., Pau, Daniel I., Whiting, Amanda L., Kim, Ye Joon, Pharoah, Blaze M., Moi, Christina, Boddy, Christopher N., Bernal, Federico
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151150/
https://ncbi.nlm.nih.gov/pubmed/29887265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.05.007
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