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O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1

The leading cause of death in cancer patients is metastasis, for which an effective treatment is still necessary. During metastasis, cancer cells aberrantly express several glycans that are correlated with poor patient outcome. This study was aimed toward exploring the effects of O-GlcNAcylation on...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncogene
Hauptverfasser: Phoomak, Chatchai, Silsirivanit, Atit, Park, Dayoung, Sawanyawisuth, Kanlayanee, Vaeteewoottacharn, Kulthida, Wongkham, Chaisiri, Lam, Eric W.-F., Pairojkul, Chawalit, Lebrilla, Carlito B., Wongkham, Sopit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151127/
https://ncbi.nlm.nih.gov/pubmed/29915392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0366-1
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