Terminal fucose mediates progression of human cholangiocarcinoma through EGF/EGFR activation and the Akt/Erk signaling pathway

Aberrant glycosylation is recognized as a cancer hallmark that is associated with cancer development and progression. In this study, the clinical relevance and significance of terminal fucose (TFG), by fucosyltransferase-1 (FUT1) in carcinogenesis and progression of cholangiocarcinoma (CCA) were dem...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Indramanee, Somsiri, Sawanyawisuth, Kanlayanee, Silsirivanit, Atit, Dana, Paweena, Phoomak, Chatchai, Kariya, Ryusho, Klinhom-on, Nathakan, Sorin, Supannika, Wongkham, Chaisiri, Okada, Seiji, Wongkham, Sopit
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872661/
https://ncbi.nlm.nih.gov/pubmed/31754244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53601-8
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