Chronic Adrenergic Signaling Causes Abnormal RNA Expression of Proliferative Genes in Fetal Sheep Islets

Intrauterine growth restriction (IUGR) increases the risk of developing diabetes in later life, which indicates developmental programming of islets. IUGR fetuses with placental insufficiency develop hypoxemia, elevating epinephrine and norepinephrine (NE) concentrations throughout late gestation. To...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Kelly, Amy C, Bidwell, Christopher A, Chen, Xiaochuan, Macko, Antoni R, Anderson, Miranda J, Limesand, Sean W
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150948/
https://ncbi.nlm.nih.gov/pubmed/30124804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00540
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