Citrullination Inactivates Nicotinamide-N-methyltransferase

Nicotinamide-N-methyl transferase (NNMT) catalyzes the irreversible methylation of nicotinamide (NAM) to form N-methyl nicotinamide (MeNAM) using SAM as a methyl donor. NNMT is implicated in several chronic disease conditions, including cancers, kidney disease, cardiovascular disease, and Parkinson’...

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Pubblicato in:ACS Chem Biol
Autori principali: Nemmara, Venkatesh V., Tilvawala, Ronak, Salinger, Ari J., Miller, Lacey, Nguyen, Son Hong, Weerapana, Eranthie, Thompson, Paul R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150842/
https://ncbi.nlm.nih.gov/pubmed/30044909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00578
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